New Drugs


Updated Monthly Feb 98

This page is written by a doctor about new and useful drugs which are now on the market


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Amias (Candesartan Cilexetil)

Is an angiotensin II antagonist and is indicated for the treatmant of essential hypertension.It binds tightly to the receptor site so only a single dose is needed for 24 hour control and has been found safe in long term trials . For more info email
Abrown5326@aol.com


Protium ( pantoprazole)

A proton pump inhibitor which cuts stomach acidity and heals stomach ulcers . It has a fast onset of action and does not affect liver enzymes so there is minimal risk of interaction with other drugs. It is given as a single dose of 40mg a day.

Gopten( trandocapril)

An ACE inhibitor with one of the longest half lives of 16-24 hours. It has dual excretion through liver and kidneys and so suits all patients. It is given as a 2mg once daily.

Morcap SR

This is a capsule form of morphine which is long lasting , most patients need only dose a day which can vary from 20 to 200 mg daily.

Aricept

A new drug which delays the onset of memory related symptoms in the elderly suffering from Dementia by about a year. More details later.

Protium- a proton pump inhibitor

- Fast and effective relief in reflux oesophagitis and peptic ulcer disease. - No known drug to drug interactions
- 2 million patients treated worldwide to date
- Enteric coated tablet formulation containing pantoprazole sodium sesquihydrate 45.1mg (equivalent to Pantoprazole 40mg)
- 3 year shelf life
- Easy to read patient information leaflet
- 40mg dose suitable for the vast majority of patients
- No dose adjustment required for the elderly or renally impaired
- Easy to swallow tablet, should be taken whole with water before or during breakfast
- Bioavailability of Protium unaffected by intake of food or antacids
- Well tolerated
- Basic NHS price: 28 x 40mg tablets 29.76


Premique
This gives period free H.R.T. For women at least one year postmenopausal

Premique Cycle
A Conjugated Oestrogens & M.P.A. - Monthly Bleed H.R.T. It has all the Benefits of PPC with less side effects.

Efexor
An Andidepressant that selectively inhibits the reuptake of Noradrenaline and Serotonin.
It has a good side effect profile, is safe in overdose and has fewer drug interactions.


Oestrogel for HRT (Bristol Myers) can be applied as a cream daily for women who cant tolerate oral pills or the patch.

Preservex ( aceclofenac- Bristol Myers) 100mg bd is a new non steroidal reported to cause fewer side effects than others of this class.

Remedine from NAPP fill the gap between paracetamol and opiates . It is a combination of dihydrocodeine and paracatemol

Tritace (Ramipril-Hoechst) from 1.25 to 10mg is a one a day ace useful in heart failure, post MI , hypertension and has a very low incidence of cough.

Istin (Amilodipine-Pfizer) at 5 or 10mg a once daily is a calcium channel blocker useful in angina and hypertension.

Lustral (sertraline -H) an SSRI is very useful in the elderly for depression especially that accompanied with anxiety.

Difflucan (H) is a one tablet treatment for vaginal thrush (not in pregnancy) .